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Effect of nutritional status on clinical outcomes in elderly patients with hepatic cirrhosis

  

  1. Department of Gastroenterology, Chongqing Renji Hospital, University of Chinese Academy of Sciences,
    Chongqing No.5 People's Hospital, Chongqing 400062, China
  • Online:2019-02-20 Published:2019-02-20
  • Contact: Corresponding author: Hao Yaqin, Email: liuyue291515@158.com

Abstract: Objective  To explore the effect of nutritional status on clinical outcomes in elderly patients with hepatic cirrhosis.Methods  A total of 465 patients with liver cirrhosis was collected from November 2012 to July 2018, including 236 elderly patients with hepatic cirrhosis. Nutritional risk screening 2002 (NRS2002) was used to evaluate the nutritional risk of elderly inpatients with liver cirrhosis, and the patients were divided into the survival group and the death group according to the prognosis, logistic regression model analysis was used to evaluate the risk factors influencing the prognosis of patients.Results  The mortality rate of elderly inpatients with hepatic cirrhosis suffering nutritional risk was significantly higher than that of those without nutritional risk (P<0.05). Compared with the survival group, MELD score, NRS2002 score, serum albumin, serum sodium and Child Pugh grading in the death group was significantly different (P<0.05). Multivariate analysis showed that endstage liver disease model (MELD) score, prothrombin time, serum sodium, Child Pugh grading and gastrointestinal bleeding were independent risk factors for death in elderly hospitalized patients with hepatic cirrhosis suffering nutritional risk. Conclusion  The elderly patients with hepatic cirrhosis have a high incidence of nutritional risk and death during hospitalization. MELD score, aprothrombin time, serum sodium, Child Pugh grading and gastrointestinal bleeding are independent risk factors for death of elderly patients with hepatic cirrhosis suffering nutritional risk. Therefore, nutritional assessment and treatment in elderly patients with hepatic cirrhosis should be paid attention.

Key words: liver cirrhosis;nutrition risk, nutrition assessment