Clinical Focus ›› 2021, Vol. 36 ›› Issue (7): 600-603.doi: 10.3969/j.issn.1004-583X.2021.07.004

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Application of BNP, Hcy, AVP, CPT in disease development and efficacy evaluation of patients with chronic pulmonary heart disease

Wei Qingyuana(), Yin Xufangb, Li Jiaojiaob   

  1. a. Department of Respiratory Medicine; Luohe Second People's Hospital, Luohe 462000, China
    b. Department of Geriatrics Luohe Second People's Hospital, Luohe 462000, China
  • Received:2021-03-25 Online:2021-07-20 Published:2021-07-23
  • Contact: Wei Qingyuan E-mail:Tsjt2003@163.com

Abstract:

Objective To investigate the value of brain natriuretic peptide(BNP), homocysteine(Hcy), arginine vasopressin(AVP), and copeptin(CPT) in disesae development and efficacy evaluation of patients with chronic pulmonary heart disease(CPHD).Methods Totally 80 CPHD patients, including 42 in remission stage and 38 in exacerbation phase were enrolled from January 2020 to January 2021, 60 patients without CPHD, who came to our hospital for a physical examination at the same time, were served as control group. BNP, Hcy, AVP, CPT of all patients were obtained. Low flow oxygen, clear airway, and heart failure control as well as other therapies were performed in CPHD patients, and BNP, Hcy, AVP, CPT of those 80 CPHD patients were recorded before and after treatment.Results BNP, Hcy, AVP, CPT of CPHD patients were significantly higher than those of without CPHD patients. Before treatment for CPHD patients, BNP, Hcy, AVP, CPT in exacerbation phase were higher than those in remission stage (P<0.05), but they were significant decrease in all CPHD patients after treatment, while the items were still higher in exacerbation phase than in remission stage (P<0.05).Conclusion Compared with those without CPHD, BNP, Hcy, AVP, CPT of CPHD patients were significantly higher with disease development, strengthened inspection will be beneficial to CPHD patients.

Key words: pulmonary heart disease, brain natriuretic peptide, homocysteine, arginine vasopressin, copeptin

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