Clinical Focus ›› 2022, Vol. 37 ›› Issue (2): 133-136.doi: 10.3969/j.issn.1004-583X.2022.02.007

Previous Articles     Next Articles

Predictive value of lung ultrasonography on adjusted therapeutic regimen for patients with pneumonia

Yu Xin1, Liu Zhongyang1,2()   

  1. 1. Postgraduate Training Base, The 967 Hospital of the Joint Logistic Support Force of the Chinese People's Liberation Army, Jinzhou Medical University, Dalian 116000, China
    2. Department of Respiratory Medicine, The 967 Hospital of the Joint Logistic Support Force of the Chinese People's Liberation Army, Dalian 116000, China
  • Received:2021-10-24 Online:2022-02-20 Published:2022-03-04
  • Contact: Liu Zhongyang


Objective To explore the clinical value of pulmonary ultrasonography on adjusted anti-infection therapeutic regimen for patients with pneumonia.Methods Ninety six patients with pneumonia admitted to the Department of Respiratory Medicine of the 967 Hospital of the People's Liberation Army from December 1, 2019 to February 28, 2021 were recorded consecutively; and lung ultrasound scores (LUS), high-sensitivity C-reactive protein (hs-CRP), white blood cell count (WBC), neutrophil percentage (NEU%), clinical symptoms and antibiotic treatment regimen were recorded respectively on admission and the 3rd Day of treatment. Patients were divided into adjusted group and unadjusted group based on adjusted antibiotics on the 3rd Day of treatment. The change in LUS on admission and the 3rd Day of treatment were compared in groups, and the factors of adjustments on antibiotics were analyzed. Patients were divided into two groups including the ΔLUS≥0 group and ΔLUS<0 group based on the difference in change of LUS (ΔLUS) on the 3 rd Day, and the prognosis of patients in two groups was observed. Results (1) LUS of patients in the adjusted antibiotics group increased after treatment, while the unadjusted group decreased. The difference in LUS between groups before treatment was statistically significant (P=0.089), the difference on the 3rd Day of treatment was statistically significant (P<0.05). (2) Logistic regression analysis showed that ΔLUS (P=0.000; OR=1.563, 95%CI: 1.229-1.987) and difference in hs-CRP (Δhs-CRP)(P=0.001; OR=1.045, 95%CI: 1.018-1.074) were associated with antibiotic adjustment. (3) The predictive value of ΔLUS on antibiotic adjustment was analyzed by receiver operating characteristic (ROC) curve. The results showed the sensitivity, specificity, and the area under ROC curve (AUC) were 81.3%, 82.8%, and 0.806, respectively. AUC was 0.901 after combination of ΔLUS and Δhs-CRP, being greater than ΔLUS and Δhs-CRP, and the predictive value was higher. Conclusion Pulmonary ultrasonography is eligible to be used as one of auxiliary references for adjusted therapeutic regimen, and it is more effective to adjust the therapeutic regimen of pneumonia patients by combining hs-CRP.

Key words: pneumonia, lung ultrasound score, treatment

CLC Number: